Stroke 7.0 - Hemorrhagic Transformation in Ischemic Stroke
Occurs when peripheral blood extravasates across a disrupted blood brain barrier (BBB) into the brain following ischemic stroke
Common complication of ischemic stroke that is often exacerbated by reperfusion with alteplase (rtPA) or endovascular therapy (EVT)
Increased time from stroke onset is associated with larger core volumes, a higher degree of vascular disruption, and therefore a higher risk of hemorrhagic transformation.
Increased time from ischemia onset to reperfusion has been associated with an increased risk of hemorrhagic transformation.
Content: